Engineering of Extracellular Vesicles as Nano Therapy for Breast Cancer

Extracellular vesicles are membrane-derived nanoparticles that represent a novel mechanism of cell-to-cell communication. It is well reported EVs play central role in the tumor microenvironment by mediating intercellular signaling among cancer cells. This has resulted development therapeutic strategies targeting various EV pathways cancer. However, because their small size and endogenous origin, they have been extensively explored for drug delivery. Hence, owing to natural ability mediate communication, high stability, low immunogenicity, emerged as an attractive platform treatment. limited production insufficient loading with moieties some issues constraining clinical translation. In this chapter, recent research studies performed attempt develop biomarkers or delivery systems will be discussed. Further, it also discuss such direct indirect cell surface modification, which can employed make successful therapeutics. Furthermore, highlight current completed trials using naturally derived